In Anlehnung an die VARC-3-Kriterien sind schwere vaskuläre Komplikationen zu dokumentieren:

„Any aortic dissection or aortic rupture
OR
Vascular (arterial or venous) injury (perforation, rupture, dissection, stenosis, ischaemia, arterial or venous thrombosis including pulmonary embolism, arterio-venous fistula, pseudoaneurysm, haematoma, retroperitoneal haematoma, infection) or compartment syndrome resulting in death, VARC type ≥2 bleeding, limb or visceral ischaemia, or irreversible neurologic impairment
OR
Distal embolization (non-cerebral) from a vascular source resulting in death, amputation, limb or visceral ischaemia, or irreversible end-organ damage
OR
Unplanned endovascular or surgical intervention resulting in death, VARC type ≥2 bleeding, limb or visceral ischaemia, or irreversible neurologic impairment
OR
Closure device failure resulting in death, VARC type ≥2 bleeding, limb or visceral ischaemia, or irreversible neurologic impairment“

Quelle: Valve Academic Research Consortium 3: updated endpoint definitions for aortic valve clinical research. VARC-3 Writing Committee (2021). European Heart Journal 42 (19), 1825-1857 (S. 2724)